1. If uremia is untreated or if complications occur, metabolic acidosis can become decompensated. What change occurs in serum pH at this point, and what is the effect on overall cell metabolism in the...

1. If uremia is untreated or if complications occur, metabolic acidosis can become decompensated. What change occurs in serum pH at this point, and what is the effect on overall cell metabolism in the body?

2. Why is there an increased risk of drug toxicity in the later stages of renal failure?

3.G.R. is hospitalized and treated with steroid medication and emergency hemodialysis. Four days later he begins to void large volumes of urine.

1. What is the significance of diuresis in this case?

2. What can G.R. expect in the future; what changes need to be made in regard to his work to prevent recurrence of acute renal failure or the development of chronic renal failure in the future?