1. Draw a simplified model of a cis-regulatory element with multiple trans-acting factors up-regulating gene expression. Your simplified model must include: a double-stranded DNA molecule labeled with...


1. Draw a simplified model of a cis-regulatory element with multiple trans-acting factors<br>up-regulating gene expression.<br>Your simplified model must include:<br>a double-stranded DNA molecule labeled with its appropriate orientation (3' and<br>5', etc.),<br>an area of DNA highlighting the gene of interest to be transcribed,<br>a highlighted area showing the promoter region,<br>one cis-regulatory element upstream of the promoter with its specific<br>transcription factor<br>• RNApol + a general transcription factor + a TATA binding protein all bound to the<br>appropriate area (think about where these bind before transcription starts),<br>an upstream enhancer with its transcription factor bound to it,<br>• and finally the TSS.<br>All parts must be labeled and in the correct area to earn full credit. **I suggest using<br>different colors for this drawing problem**.<br>

Extracted text: 1. Draw a simplified model of a cis-regulatory element with multiple trans-acting factors up-regulating gene expression. Your simplified model must include: a double-stranded DNA molecule labeled with its appropriate orientation (3' and 5', etc.), an area of DNA highlighting the gene of interest to be transcribed, a highlighted area showing the promoter region, one cis-regulatory element upstream of the promoter with its specific transcription factor • RNApol + a general transcription factor + a TATA binding protein all bound to the appropriate area (think about where these bind before transcription starts), an upstream enhancer with its transcription factor bound to it, • and finally the TSS. All parts must be labeled and in the correct area to earn full credit. **I suggest using different colors for this drawing problem**.

Jun 11, 2022
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