[1] Below is raw data of genotype frequencies at the single nucleotide polymorphism (SNP) locus rs9967044 on Chromosome 18 in humans. Data for two subpopulations is presented: Tokyo, Japan and the...


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[1] Below is raw data of genotype frequencies at the single nucleotide polymorphism (SNP) locus<br>rs9967044 on Chromosome 18 in humans. Data for two subpopulations is presented: Tokyo, Japan and<br>the Luhya of Kenya.<br>Genotype<br>СТ<br>СС<br>TT<br>Luhya<br>0.919<br>0.081<br>0.000<br>Tokyo<br>0.442<br>0.433<br>0.125<br>In another region of Chromosome 18, there is another SNP (rs2469898). In this case only allele<br>frequencies are reported for the Luhya and Tokyo populations (below).<br>Allele<br>C<br>T<br>Luhya<br>Tokyo<br>0.63<br>0.37<br>0.14<br>0.86<br>Calculate and report FST for each SNP locus separately. Why may FST be different between regions on<br>the same chromosome?<br>

Extracted text: [1] Below is raw data of genotype frequencies at the single nucleotide polymorphism (SNP) locus rs9967044 on Chromosome 18 in humans. Data for two subpopulations is presented: Tokyo, Japan and the Luhya of Kenya. Genotype СТ СС TT Luhya 0.919 0.081 0.000 Tokyo 0.442 0.433 0.125 In another region of Chromosome 18, there is another SNP (rs2469898). In this case only allele frequencies are reported for the Luhya and Tokyo populations (below). Allele C T Luhya Tokyo 0.63 0.37 0.14 0.86 Calculate and report FST for each SNP locus separately. Why may FST be different between regions on the same chromosome?

Jun 11, 2022
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